The purpose of the present study was to analyze the immunohistochemical CD10 expression in the stromal cells in invasive breast cancer and the association of the CD10 expression with several prognostic markers such as the age of the patient, size of the tumor, lymph node status, histological grade, stage of the tumor, and HER2-neu, PR, and ER status. This evidence concerns the gene ERBB2 and invasive breast carcinoma.