ZBTB16 and lupus nephritis: In the comparison of 62 subgroups, the up-regulated gene (PTPRC, MX1) and the down-regulated DEGs (EGR1, MME, RORC, ZBTB16, FKBP5) were verified to have mostly consistent change trends in all Lupus Nephritis vs. Normal Kidneys group with the results of GSE200306 (Fig. 3).