In the comparison of 62 subgroups, the up-regulated gene (PTPRC, MX1) and the down-regulated DEGs (EGR1, MME, RORC, ZBTB16, FKBP5) were verified to have mostly consistent change trends in all Lupus Nephritis vs. Normal Kidneys group with the results of GSE200306 (Fig. 3). This evidence concerns the gene MME and lupus nephritis.