Univariate and multivariable predictors of the primary outcome are demonstrated in Extended Data Tables 1 and 2 and included age (odds ratio (OR) = 1.07, 95% confidence interval (CI) = 1.05, 1.09), overt ischemic heart disease (IHD; OR = 1.52, 95% CI = 1.15, 2.02) and log(N-terminal pro-brain natriuretic peptide (NT-proBNP)) (OR = 1.69, 95% CI = 1.46, 1.96). Here, NPPB is linked to myocardial ischemia.