Published studies from our group [12, 21–23] further established Kindlin-2 as a major driver of the invasion-metastasis cascade in TNBC, influencing epithelial-to-mesenchymal transition (EMT), cancer cell senescence, chemotherapeutic sensitization, and actin-mediated integrin outside-in signaling [12, 21–23]. Here, FERMT2 is linked to cancer.