NOTCH1 and acute lymphoblastic leukemia: To address this question, we first performed super-resolution radial fluorescence (SRRF) microscopy to achieve nanometer-scale spatial resolution of either nuclear N1ICD condensates or endogenous Notch1 condensates in T-ALL cells (Fig. 3D, Extended Data Fig. 6, Extended Data Fig. 7, Movies 4, 5)61–63.