Other pathways indicative of neurodegeneration (gene sets, Pathways of neurodegeneration, Parkinson disease, Huntington disease, Amyotrophic lateral sclerosis, Alzheimer's disease) were also downregulated in L5 ET, L5 IT, L6 CT, L4 IT, L6b, L6 ITCar3, Chandelier, Sst, Vip, and Lamp5Lhx6 neurons. Here, SST is linked to early-onset autosomal dominant Alzheimer disease.