RAB38 and Alzheimer disease: We found Rab genes (known to regulate autophagy by the Rab GTPase network; Ao et al., 2014), RAB37 and RAB38, are significantly upregulated in early AD (log-fold change of 2.02 in Sst Chodl cells and 2.03 in endothelial cells, respectively); autophagy-related genes were also observed in Mathys et al. (2023) to be associated more with early AD changes relative to late AD.