The autophagy-related gene (ATG) family has more than 35 members, which play variousroles in human diseases(33).Studies have shown that ATG7 loss can induce oxidative stress andendoplasmic reticulum stress(34).Kozhevnikova et al. found that levels of ATG7 protein weresignificantly reduced in rats with advanced retinopathy compared with age-matchedcontrol rats(35). The gene discussed is ATG7; the disease is retinal disorder.