Beyond imaging, various prognostic criteria on ICU admission include older age, male sex, diabetes, obesity, high blood pressure, immunosuppression, severity of hypoxemia, lymphopenia[10–13], elevated plasma biomarkers of non-specific inflammation such as C-reactive protein (CRP) and ferritin levels [10–12, 14, 15], and of specific inflammation cytokines such as interleukin 1 (IL-1)) [10–12, 15], interleukin 6 (IL-6) [10, 11, 16, 17], and standard coagulation test results indicative of hypercoagulability [18]. Here, CRP is linked to obesity due to melanocortin 4 receptor deficiency.