Our data (Figure 2A and B, Figure 2—figure supplement 1C), together with the fact that B-cell lymphomas occur with a higher incidence in WT C57Bl/6J female mice (Brayton et al., 2012), suggested that Trp53+/+ Eμ-Myc male mice are more refractory to B-cell lymphomas, and that p53-AS isoforms might confer this male-specific protection against lymphomagenesis. The gene discussed is TP53; the disease is B-cell non-Hodgkin lymphoma.