Our transcriptomic data from splenic cells of Trp53+/+ Eμ-Myc and Trp53ΔAS/ΔAS Eμ-Myc males disclosed very few differentially expressed genes and highlighted Ackr4 as a male-specific positive prognostic factor in Eμ-Myc-induced lymphomas. This evidence concerns the gene MYC and lymphoma.