TGFB1 and neoplasm: Of note, after 29 days, the combination of AVID200+a-PD-1 significantly reduced tumor size compared with a-PD-1 monotherapy (Figure 1B), suggesting that TGF-β-TRAP potentiates the antitumor response to a-PD-1 in this orthotopic PDAC model with metastatic liver tropism.