Furthermore, a study detected 363 differentially accumulated proteins in patients with EoE compared to healthy subjects, including eosinophil-associated proteins (e.g., RNASE2, RNASE3, SERPINC1, EPX, and PRG3) that correlated with eosinophil counts and disease severity, proposing new, minimally invasive biomarkers [101]. Here, RNASE3 is linked to eosinophilic esophagitis.