PDE6A and retinitis pigmentosa 1: The Pde6anmf363/nmf363 mice (hereafter termed Pde6a mice), which carry a missense mutation (c.2009A > G, p.D670G) in the Pde6a gene and exhibit moderate photoreceptor degeneration, has been widely used to study Pde6a‐related RP (Figure 1A).[4] The CBE system can achieve G‐to‐A base conversions within the editing window under appropriate sgRNA guidance, making it suitable for repairing this A‐to‐G mutation (Figure 1B).