However, RNA sequencing, immunoblotting, and immunostaining analyses revealed comparable transcription and translation levels among the tinnitus, control, and nontinnitus groups, suggesting that the hyperexcitability associated with tinnitus is likely mediated by abnormal KCNQ2 and KCNQ3 functioning rather than aberrant protein expression (Fig. S4). The gene discussed is KCNQ3; the disease is Tinnitus.