The ratio of neutrophils to lymphocytes, angiotensin-converting enzyme 2, total protein, blood urea nitrogen, cystatin C, potassium, phosphorus, platelet distribution width, activated partial thromboplastin time, thrombin time, and hepatitis B surface antibody are closely related to the prognosis of breast cancer (Tiainen et al., 2021; Nair et al., 2021; Li et al., 2021). The gene discussed is CST3; the disease is breast carcinoma.