The participant characteristics and various predictors identified were tested through bivariate analysis, factors such as female sex (P = .015), HIV/AIDS positive (P = .0005), hypertension (P = .035), body mass index > 30kg/m2 (P = .0005), albumin level < 30g/L (P = .0005), history of radiation therapy (P = .017), ASA III-IV score (P = .0005) and peritonitis (P = .0005) were found to be statistically significantly associated with anastomotic leakage. The gene discussed is ALB; the disease is peritonitis.