For instance, biallelic mutations in the B3GLCT gene (MIM*610308) are responsible for Peters plus syndrome in humans, a severe congenital glycosylation disorder where patients have different anomalies that include eye malformation such as Peters' anomaly, disproportionate short stature, dysmorphic facial features and developmental delay although it only generates small sized craniofacial and skeletal defects in mice and normal development in zebrafish (166, 167). This evidence concerns the gene B3GLCT and congenital disorder of glycosylation.