In this study, we found that intersection genes are trapped in IL-17 signaling pathway, aldosterone synthesis and secretion, cyclic adenosine monophosphate (cAMP), rat sarcoma (RAS), phosphoinositide 3-kinase (PI3K) Akt and mitogen-activated protein kinases (MAPK) signaling pathway, advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling pathway in diabetes complications, which is consistent with literature results. The gene discussed is AGER; the disease is diabetes mellitus.