Specifically, ALT (alanine aminotransferase) serves as a critical prognostic indicator in pregnant women with COVID-19 (Carrión-Nessi et al., 2023), and serum ALT levels are a key factor in determining pregnancy outcomes in women with hepatitis B virus infection during pregnancy (Nguyen et al., 2009; Alves and Rapp, 2023). The gene discussed is GPT; the disease is hepatitis B virus infection.