The serum FGF19 level of sepsis patients with GI dysfunction was significantly greater than that of sepsis patients without GI dysfunction when admitted to the ICU [355.1 (37.2, 2315.4) pg./mL vs. 127.4 (5.7, 944.2) pg./mL, p = 0.003]. Here, FGF19 is linked to Functional abnormality of the gastrointestinal tract.