The present study was able to highlight the main links and differences in the expressions of the molecular markers p16, p53, E-cadherin, Cyclin-D1, EGFR, and HOV E6/E7 mRNA at the level of skin epithelial lesions and cervical cancer caused by high-risk and low-risk HPV infections. The gene discussed is CCND1; the disease is cervical carcinoma.