Anaplastic lymphoma kinase (ALK) and Aurora are two commonly mutated genes in NB, and low expression of FTO was more sensitive to TAE684 (ALK inhibitor), VX-680 (pan-Aurora inhibitor), and BMS-754807 (IGF-1R/IR inhibitor, which also inhibits Aurora) (Figure 7B). This evidence concerns the gene FTO and neuroblastoma.