Analyses encompassing both GPR126 and TERT mutations across healthy controls, patients with cystitis, and patients with UBC revealed an area under the receiver operating characteristic curve (AUC) and MAF of 0.679 and 21.61, respectively, for GPR126 alone, contrast to the AUC and MAF of 0.786 and 28.29, respectively, for TERT mutations. Here, TERT is linked to cystitis.