Alterations in FGFR3 also constitute critical mutations in bladder cancer, displaying strong associations with disease stage and grade; approximately 78.1% of patients with non-invasive bladder cancer showed FGFR3 expression, whereas the expression rate dropped to 18.2% in muscle-invasive cases (Akanksha and Sandhya, 2019). The gene discussed is FGFR3; the disease is urinary bladder cancer.