ZSCAN1 and rapid-onset childhood obesity-hypothalamic dysfunction-hypoventilation-autonomic dysregulation syndrome: Furthermore, the application of PhIP-Seq for detecting ZSCAN1 autoantibodies in patients with Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD) provided further evidence to support the hypothesis that ROHHAD syndrome is a pediatric peripheral neurological disorder with neoplastic implications (Mandel-Brehm et al., 2022).