INS and diabetes mellitus: Diabetes Care., 2009, Houlden et al., 2007) The probable avoidance of macro- and micro-vascular complications due to high blood glucose and the confirmed enhancement of bodily-secreted insulin have prompted the early addition of hypoglycemic drugs like insulin.(Brown et al., 2004, Weng et al., 2008) However, the threshold for HbA1C to start insulin therapy for type-2 DM is not fully defined.