Very recently, we have showed that BCL11B promotes T-ALL cell survival via the XRCC5/C11ORF21 axis.36 These results are in line with our recent data showing better prognosis for patients with T-cell leukemia and lymphoma with BCL11B mutations.37,38 However, this research included a small number of cases with BCL11B mutations, and has to be confirmed in a larger study. Here, BCL11B is linked to lymphoma.