Research has prompted that long-term high-frequency electroacupuncture stimulation of the Dazhui and Baihui acupoints can not only prevent the degeneration of dopaminergic neurons in the substantia nigra but also upregulate the level of BDNF mRNA in the ventral midbrain field, achieving the goal of improving PD (Liang et al., 2002). The gene discussed is BDNF; the disease is Parkinson disease.