Several clinical/demographic variables in MSA patients were found to be correlated with serum IL-6 levels, including HAMA (r = 0.257, p = 0.004), HAMD (r = 0.220, p = 0.014), UMSARS I (r = 0.211, p = 0.018), UMSARS IV (r = 0.280, p = 0.002) and IADL scores (r = −0.230, p = 0.010), but not with other remaining variables. The gene discussed is IL6; the disease is multiple system atrophy.