HIF1A and ischemic stroke: Additionally, it is interesting that the expression trend of HIF‐1a is consistent in MACO female and male mice (Limatola et al., 2010), and the NF‐κB related pathway is predicted to be involved in the occurrence of ischemic stroke in women (Xie et al., 2020), suggesting that the results of our study may be generalizable to female and require further exploration.