Tumor presence increased mRNA levels of ATF4 (87.76%, p < 0.001) and GADD34 (301.20%, p < 0.001) in skeletal muscle (Figure 4a) but only GADD34 mRNA expression was induced in the heart (48.10%, p = 0.033; Figure 4b). The gene discussed is ATF4; the disease is neoplasm.