For example, of the ligand–receptor pairs pertaining fibroblasts to and myeloid cells, THBS1‐CD36, which has been reported to be associated with tumour growth and metastasis in CRC,30, 31 was significantly enriched in fibroblasts, indicating a potential role of fibroblasts from L‐CRC in promoting tumour progression. This evidence concerns the gene THBS1 and colorectal carcinoma.