To investigate the apoptosis-inducing potential and enhanced therapeutic efficacy of chemotherapeutic agents by drug administration, we examined the expression of apoptosis-related genes (Bcl-2, Bax, and caspase-3) in 4T1 cancer cells treated with DMSO, S3I-201, WJ-Exo(S3I-201), and WJ-Exo. This evidence concerns the gene BCL2 and cancer.