Our research group has previously reported on the generation of MSLN-specific T cells and NCL-specific T cells through the stimulation with self-differentiated myeloid-derived antigen-presenting cells reactive against tumor expressing either MSLN-derived dendritic cells (MSLN-SmartDCs) or NCL-derived dendritic cells (NCL-SmartDCs) [20, 28]. This evidence concerns the gene MSLN and neoplasm.