These include APOC1, APOD, CDKN2A, CTHRC1, FXYD3, INPP5F, MT2A, S100A4, SEMA3B, TMSB10 and VGF [64–67], suggesting this community is detecting genes co-regulated by drivers of a melanoma-specific cell state. This evidence concerns the gene CDKN2A and melanoma.