Nimodipine treatment for 1.5 months did not modulate endothelial expression of ICAM-1 or VCAM-1 in capillaries, arterioles or venules (Extended Data Fig. 7a–f) nor did it modulate FITC-dextran extravasation in three vehicle-treated and four nimodipine-treated mature AD mice (P = 0.6 and P = 0.8, from Mann–Whitney tests, for extravasation measured in cortex at depths <40 μm and 40–126 μm from the cortical surface, respectively). The gene discussed is VCAM1; the disease is Alzheimer disease.