Our single-cell sequencing data demonstrated that sepsis marker genes were highly elevated in CD16+ monocytes, including NAP1L1 (Freitag and Schwertz, 2022), CFD (Sommerfeld et al, 2021), BID (Weber et al, 2008), BCL2A1 (Li et al, 2022a), MALAT1 (Chen et al, 2022), RNH1 (Zechendorf et al, 2020), and LILRA5 (Ning et al, 2023) genes (Fig. 5C,D). This evidence concerns the gene LILRA5 and Sepsis.