Treatment of nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mice bearing NB tumors with an injection containing NK cells, anti-GD2 antibody, and lenalidomide was superior than the treatment without lenalidomide, with the latter blocking IL-6 and TGFβ1 signaling, thus overcoming the suppression of NK cells [103]. The gene discussed is IL6; the disease is neuroblastoma.