FTL and familial pancreatic carcinoma: To explore FTH1 and FTL expression in pancreatic cancer cells and their associations with KRAS mutation status, we analyzed FTH1 and FTL protein levels in hTERT-HPNE, KRAS-WT pancreatic cancer (BxPC-3), and KRAS-mutant pancreatic cancer (AsPC-1, Mia PaCa-2, SUIT-2, PANC-1, and PANC-1/GR) cells through Western blotting (Fig. 2a).