To investigate the role of FTH1 in pancreatic cancer cell growth in vivo, SUIT-2 cells stably transfected with control shRNA (Scr and Void) or shFTH1 shRNA (shFTH1#1 and #4) were subcutaneously injected into the posterior flank of NOD/SCID male mice s.c. The results indicated that the shCtrl group demonstrated rapid tumor growth, with the tumor size increasing to 100–150 mm3 within 1 week; thus, the tumor volume of each group was measured every 2 days starting 1 week after the injection (Fig. 3g). This evidence concerns the gene FTH1 and familial pancreatic carcinoma.