Another ferritin subunit type, FTL, exhibited low expression in KRAS-mutant cells but relatively high expression in the KRAS-WT pancreatic cancer cell line BxPC-3, indicating that variations in FTH1 and FTL expression may be key factors driving pancreatic cancer progression in patients with different KRAS mutation statuses. Here, FTH1 is linked to familial pancreatic carcinoma.