We previously reported that FTH1 is strongly expressed in many KRAS-mutant pancreatic cancer cells (Fig. 2a, b); thus, extracellular and intracellular glutamine and glutamate contents were measured to evaluate whether FTH1 is associated with a metabolic shift in glutamine metabolism (Fig. 4c). The gene discussed is FTH1; the disease is familial pancreatic carcinoma.