CD19 and systemic lupus erythematosus: Wang et.al using BCMA-CD19 compound chimeric antigen receptor T cells (cCAR) dual technique as well as case series conducted by Muller et, al shown grade 1 cytokine release syndrome proves CD19 CAR-T-cell transfer is feasible, tolerable, and highly effective in SLE; however, long-term consequences need to study more [22–24].