Bulk RNAseq analysis of human superior temporal gyrus showed a modest 20–30% upregulation of BRD4 mRNA in PSP subjects, and snRNAseq analysis in the same study suggested BRD4 upregulation was more prominent in glia than neurons, but none of these changes was statistically significant after adjustment for multiple comparisons68. Here, BRD4 is linked to supranuclear palsy, progressive, 1.