In view of our finding that Brd4 plays an important role in microgliosis and microglial synapse elimination in Tau zebrafish, we labeled human autopsy brain sections from 4 controls and 5 PSP cases with antibodies to Brd4 and Iba1 (a microglial marker) and examined expression in the substantia nigra and globus pallidus, two areas affected prominently by PSP pathology1,5. Here, BRD4 is linked to supranuclear palsy, progressive, 1.