CFTR and chronic obstructive pulmonary disease: A study of a murine P. aeruginosa lung infection model demonstrated an association between NE and CFTR degradation (figure 1), thus establishing a link between NE activity and loss of CFTR function in bacterial lung infections relevant to CF [60]; this could lead to impairment in airway ion transport in other chronic inflammatory lung diseases in which CFTR has been implicated, such as COPD [61].