TRIM21 and Skin ulcer: And between the two groups, gender, DM-associated skin vascular lesions such as Mechanic hand, heliotrope rash, Gottron’s sign, shawl sign, periungual erythema, Raynaud phenomenon, skin ulcer, and V sign were no significant statistical differences, nor were there differences in autoantibodies such as ANA, RF, and RO52 (Table 1).