Consequently, triple immunostaining for Cx43, Cx47, and CC1 revealed a marked loss of Cx43-Cx47 colocalization in CC1 + oligodendrocytes in both gray and white matter areas of the spinal cord in MHV-A59-infected mice compared to controls at the acute infection stage (5 days pi, Fig. 7A–H). Here, GJC2 is linked to infection.