,22 Note that a combination of PPE59 IgA plus 16kda IgG brings sensitivity to 74%, and adding the results of other rapid tests (SM = 66%) raises it to 86.5% (at 88.9 % specificity), making this combination a potential target product profile for composing rapid diagnosis tests in low-income areas highly burdened with TB. The gene discussed is CD79A; the disease is tuberculosis.