TG and hyperthyroidism: Hyperthyroidism is a common endocrine disease, impacting at least 2.5% of adults all over the world, characterized by hypermetabolism and multiple organ dysfunction.44 Thyroid function is already known to have a strong and profound influence on the cardiovascular system; receptors for thyroid hormone are found in both vascular and myocardial endothelial tissues, and minute changes in circulating thyroid hormones concentrations can cause cardiovascular system effects.