Several candidates identified in our experiment, either in CuCl2-or CuCl2 and LA-treated groups, are directly involved in cancerogenesis (such as MEMO1, ATOX1, L1CAM, RABGGTA, MAP2K7 and others, (Supplementary Tables 1, 2) and may be of potential interest for anti-cancer research. The gene discussed is ATOX1; the disease is cancer.