Dysregulated in ALS patient, related with downregulation of miRNA (Liguori et al., 2018).hnRNPA1: miR-206 (Fu et al., 2020), miR-339 (Chen et al., 2020), miR-15a-5p and miR-25-3p (Rodriguez-Aguayo et al., 2017), miR-490 (Zhou et al., 2016), miR-18a (Fujiya et al., 2014), miR-128 (Fung et al., 2019), lncRNA MIR4435-2HG (Li et al., 2023), linc02231 (Xu et al., 2023), lncRNA ANCR (Wen et al., 2020).hnRNPA2B1: miR-30c-5p (Wu et al., 2023), miR-326 (Luo et al., 2021), miR-146b-5p (Zhang and Li, 2019), miR-369 (Konno et al., 2015), lncRNA SOX2-OT (Zhang and Li, 2019). This evidence concerns the gene SOX2 and amyotrophic lateral sclerosis.