TARDBP and frontotemporal dementia: A study using a screening system for TDP-43 aggregation in mouse neuroblastoma Neuro2a cells analyzing a library of genes associated with fALS/FTD has shown that microtubule-related proteins (MRPs) and RBPs co-aggregate with TDP-43 in the cytosol via different mechanisms, involving microtubules and LLPS, respectively.