Kasozi et al. (2018) conducted a study to examine the effect of calcium levels on s100a1 protein expression, histopathological changes in blood, hepatic and renal tissues, antioxidant activity in male Wistar rats with type 2 diabetic mellitus (T2DM) that were supplemented with amaranth grain (AG). The gene discussed is S100A1; the disease is type 2 diabetes mellitus.