After the treatment with moxibustion, the expression of cytokines changed; in other words, compared with RA group, the expression of IL-4 (60.0 ± 12) and IL-10 (114.23 ± 6.45) was increased, and the expression of IFN-γ (106.72 ± 19.34) was decreased. This evidence concerns the gene IFNG and rheumatoid arthritis.