Enhances gut barrier function, reduces liver inflammation, decreases proinflammatory markers like TNF-α and IL-6, modulates bile acid metabolism, decreases endotoxemia, increases mucin production, reduces oxidative stress, influences Kupffer cells, produces antimicrobial substances.Modulates SREBP activity, influences hepatic lipid metabolism, enhances insulin sensitivity. Here, MUC5AC is linked to serum lipopolysaccharide activity.