For instance, a study using a mouse model of FA to shrimp tropomyosin (ST) revealed that mice sensitized to ST exhibited elevated levels of ST-specific IgE and immunoglobulin G1 (sIgG1) compared to the control group, as well as displaying symptoms of anaphylaxis, including reduced and/or decreased activity accompanied by increased respiratory rates, wheezing, and labored respiration (Fu et al., 2017). The gene discussed is IGHE; the disease is anaphylaxis.